While the exact ingredients of Fernet-Branca are a well-kept secret, Memorie di Angelina claims it includes “aloe, gentian root, rhubarb, gum myrrh, red cinchona bark, galangal, camomile, cinnamon, saffron, iris, bitter orange, and white turmeric.” Though it’s widely considered an acquired taste, its high acidity is thought to aid digestion.